The rapper made a cameo in Anchorman 2: The Legend Continues last year and is now desperate to land a major role in another hilarious blockbuster.
A source told the US' OK! magazine: "He's told his agent to find him a role in a big comedy, but so far no one is interested."
The Bound 2 hitmaker, 37 - who has 14-month-old daughter North with his wife Kim Kardashian - has been keen to embark on a film career for a while, but he's always insisted he's "waiting for the right part."
An insider told 'Dish Nation' recently: "He really wants to make a name for himself as a comedic actor - in his mind, he's convinced that he's a very funny guy.
"The general perception of Kanye is that he takes himself way too seriously, but he says that's only when it comes to his music."
Meanwhile, Kanye is keen to focus on his upcoming album and has even told Kim, 33, that he doesn't want another child at the moment as he's trying to arrange another world tour for after the release.
A source said previously: "Kim has made no secret for her desire to get pregnant right away with another baby. However, Kanye is resisting because he is going to be going on a worldwide tour after the release of his upcoming album."